40. Breast Cancer Show Ever (Season 12, Episode 09)
There’s something very Batman about this episode, and females might like it for being one of the few episodes taken from the perspective of a girl even though the ending doesn’t give her a classic heroine’s triumph, though very few characters in South Park get that kind of honour too often. I like this one for sticking up for a good cause and a healthy state of mind and spirit.
“I was wrong to make fun of breast cancer, and I’m very remorsefulness.” -Cartman